Zoetis EAZI-BREED CIDR
By Zoetis
Last reviewed: January 2024
EAZI-BREED CIDR (Controlled Internal Drug Release) is Zoetis's intravaginal progesterone-releasing insert that revolutionized estrous synchronization in dairy a
What is EAZI-BREED CIDR?
EAZI-BREED CIDR is an intravaginal insert containing 1.38 grams of progesterone in a silicone elastomer molded over a nylon spine. When inserted into the vagina, the CIDR releases progesterone continuously over 7 days, mimicking the progesterone phase of the estrous cycle.
How Progesterone Controls the Cycle
Progesterone is the dominant hormone during the luteal phase (days 4-17 of the 21-day cycle). High progesterone:
When progesterone falls (naturally at luteolysis or upon CIDR removal), the cow is "released" to come into estrus within 2-3 days.
The CIDR Advantage
Adding CIDR to synchronization protocols provides several benefits:
Common CIDR Protocols
7-Day CIDR + PG Protocol (Heifers):
5-Day CO-Synch + CIDR (Cows):
Ovsynch + CIDR (Problem Breeders):
Key Features
- Controlled Progesterone Release: Consistent 1.38g progesterone delivery over 7 days
- Flexible T-Shape Design: Easy insertion and retention with minimal vaginal irritation
- Tail for Easy Removal: Attached nylon tail allows simple extraction at protocol end
- Single-Use Convenience: Each CIDR is individually packaged and sterile
- Universal Applicator: EAZI-BREED Applicator sold separately for hygienic insertion
Advanced Features
- Induces Cyclicity: Brings anestrous cows into cycling status for breeding
- Ovarian Reset: Causes turnover of dominant follicle for improved oocyte quality
- Protocol Versatility: Compatible with Ovsynch, CO-Synch, and custom protocols
- Heifer-Friendly: Sized appropriately for virgin heifers
- Proven Research Base: Thousands of published studies validating CIDR protocols
Ideal For
Competitive Advantages
What sets EAZI-BREED CIDR apart from alternatives:
- EAZI-BREED CIDR advantages: 1. **Market Leader**: The original and most trusted progesterone insert worldwide 2. **Research Foundation**: More published research than any competing product 3. **Zoetis Integration**: Works seamlessly with LUTALYSE and FACTREL for complete protocols 4. **Consistent Quality**: Reliable progesterone release curve batch after batch 5. **Technical Support**: Access to Zoetis reproduction specialists 6. **Global Experience**: Protocols refined across millions of cattle worldwide
Pricing Information
Here is the pricing information for EAZI-BREED CIDR:
Pros & Considerations
- Industry gold standard for progesterone supplementation
- Induces cyclicity in anestrous cows
- Improves fixed-time AI success rates
- Well-tolerated with minimal side effects
- Compatible with all major sync protocols
- Extensive research support
- Requires handling cattle twice (insertion and removal)
- Small percentage of CIDRs may be lost (1-3%)
- Causes some vaginal mucus discharge (normal)
- Not for use in cattle intended for food within 7 days
- Single-use only (do not reuse)
- Requires additional hormones for complete protocol
Implementation & Setup
How to implement EAZI-BREED CIDR on your dairy operation:
Training & Support
Training and support options available for EAZI-BREED CIDR:
Evaluation Questions
Key questions to consider when evaluating EAZI-BREED CIDR:
- 1. What is our current 21-day pregnancy rate and heat detection rate? 2. What percentage of cows are not cycling by voluntary waiting period end? 3. Are we using timed AI or heat detection-based breeding? 4. How many cows are handled at each reproductive event? 5. What is our current synchronization protocol? 6. Do we have adequate cattle handling facilities for CIDR insertion? 7. Are breeding technicians trained on CIDR protocols? 8. What are our conception rates by service number?