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Zoetis Fertagyl

By Zoetis

Last reviewed: January 2024

Fertagyl (gonadorelin) is Zoetis's alternative GnRH product for inducing ovulation and treating ovarian cysts in dairy and beef cattle. Containing gonadorelin a

What is Fertagyl?

Fertagyl is a sterile aqueous solution of gonadorelin acetate for injection in cattle. Like FACTREL, Fertagyl is a synthetic GnRH analog that stimulates the release of luteinizing hormone (LH) from the anterior pituitary gland.

Equivalent to FACTREL

Fertagyl and FACTREL both contain gonadorelin and work identically in reproductive protocols. Choice between products often depends on:

  • Pricing and availability
  • Packaging preferences
  • Veterinarian recommendation
  • Supply chain considerations
  • Mechanism of Action

    Gonadorelin in Fertagyl:

  • Binds to GnRH receptors on pituitary gonadotrophs
  • Triggers rapid release of stored LH
  • Causes ovulation of mature dominant follicle
  • Initiates new follicular wave development
  • Indications

  • Ovulation induction in timed AI protocols
  • Treatment of ovarian follicular cysts
  • Post-breeding ovulation insurance
  • Follicular wave synchronization
  • Key Features

    • Synthetic GnRH: Gonadorelin acetate for reliable LH release
    • Standard Dosing: 2 mL per cow delivers effective GnRH dose
    • IM Administration: Intramuscular injection in neck or hindquarter
    • Multi-Dose Vials: Various vial sizes for herd size flexibility
    • Protocol Compatible: Interchangeable with FACTREL in all protocols

    Advanced Features

    • Ovulation Induction: Predictable ovulation 24-32 hours post-injection
    • Cyst Treatment: Effective for follicular cyst luteinization or regression
    • Wave Recruitment: Initiates new follicle wave for synchrony
    • No Withdrawal: Zero milk and meat withdrawal periods

    Ideal For

    Competitive Advantages

    What sets Fertagyl apart from alternatives:

    • Fertagyl advantages: 1. **Zoetis Brand**: Same quality standards as all Zoetis products 2. **Protocol Flexibility**: Direct substitute in any GnRH protocol 3. **Pricing Options**: May offer cost advantages in some markets 4. **Proven Efficacy**: Established track record globally

    Pricing Information

    Here is the pricing information for Fertagyl:

    Pros & Considerations

    Advantages:
    • Equivalent efficacy to FACTREL
    • Same indications and protocol use
    • Zoetis quality manufacturing
    • No withdrawal period
    • May offer price advantages
    Considerations:
    • Same limitations as any GnRH product
    • Requires refrigeration
    • Response depends on ovarian status
    • Precise timing needed in protocols

    Implementation & Setup

    How to implement Fertagyl on your dairy operation:

    Training & Support

    Training and support options available for Fertagyl:

    Evaluation Questions

    Key questions to consider when evaluating Fertagyl:

    1. 1. Are we currently using FACTREL or another GnRH product? 2. What is our per-dose GnRH cost? 3. Is Fertagyl available through our supplier at competitive pricing? 4. Are protocols established that specify product or allow substitution? 5. Do veterinarians/consultants have preference for specific GnRH?

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    About Zoetis

    Learn more about Zoetis and their complete product lineup on their company profile page.

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