Zoetis LUTALYSE
By Zoetis
Last reviewed: January 2024
LUTALYSE (dinoprost tromethamine) is Zoetis's original prostaglandin F2α product, the gold standard for estrous synchronization and reproductive management in d
What is LUTALYSE?
LUTALYSE is a synthetic prostaglandin F2α (PGF2α) identical to the natural hormone produced by the uterus. It causes:
Mechanism of Action
When injected, LUTALYSE:
Standard vs. HighCon
Both contain the same amount of active ingredient; HighCon simply requires smaller injection volume.
Primary Applications
Estrous Synchronization: Foundation of Presynch-Ovsynch and other TAI protocols
Heat Induction: Bringing cycling cows into heat for AI
Pyometra Treatment: Causes uterine contractions and expulsion
Abortion Induction: When needed for management purposes
Mummified Fetus: Helps expel mummified calves
Key Features
- Proven Efficacy: Decades of field use and research validation
- Predictable Response: 2-5 day interval to estrus after injection
- Versatile Applications: Sync protocols, pyometra, abortion induction
- Compatible with GnRH: Works in Ovsynch and related protocols
- Economic Value: Affordable reproductive management tool
Advanced Features
- Natural Hormone Analog: Identical to endogenous PGF2α
- Rapid Absorption: Intramuscular injection for quick uptake
- Short Half-Life: Clears system quickly, minimal residue concerns
- Field-Proven Protocols: Validated in thousands of research studies
- Combination Flexibility: Works with CIDR, GnRH, and other reproductive tools
Ideal For
Competitive Advantages
What sets LUTALYSE apart from alternatives:
- LUTALYSE advantages: 1. **Original Brand**: The first and most recognized prostaglandin 2. **Extensive Research**: More published studies than any prostaglandin 3. **Predictable Results**: Consistent response in properly staged cows 4. **Zoetis Quality**: Reliable manufacturing and quality control 5. **Protocol Flexibility**: Foundation of virtually all TAI programs 6. **Proven Track Record**: Decades of successful reproductive outcomes
Pricing Information
Here is the pricing information for LUTALYSE:
Pros & Considerations
- Gold standard prostaglandin with extensive research
- Predictable response in cycling cattle
- Foundation of all modern sync protocols
- Affordable and widely available
- Compatible with all reproductive programs
- Only effective on cows with functional CL (day 6-17)
- Larger injection volume than HighCon (5 mL vs 2 mL)
- Requires proper staging for optimal response
- Not effective on anestrous cows without progesterone priming
- Human safety: Women should not handle if pregnant
Implementation & Setup
How to implement LUTALYSE on your dairy operation:
Training & Support
Training and support options available for LUTALYSE:
Evaluation Questions
Key questions to consider when evaluating LUTALYSE:
- 1. What is our current reproductive protocol? 2. Are we properly staging cows before prostaglandin injection? 3. What is our heat detection rate post-prostaglandin? 4. Should we consider HighCon for smaller injection volume? 5. How are we training staff on safe handling? 6. What is our protocol compliance rate?