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Zoetis Orbeseal Teat Sealant

By Zoetis

Last reviewed: December 2025

Orbeseal provides non-antibiotic dry cow protection through internal teat sealant that physically prevents bacterial entry during the dry period.

Overview

Orbeseal is an internal teat sealant containing bismuth subnitrate in a mineral oil base. It provides non-antibiotic dry period protection by forming a physical barrier in the teat canal.

How It Works

Unlike antibiotics that kill bacteria, Orbeseal:

  • Forms a physical plug in the teat canal
  • Persists throughout the dry period
  • Prevents new bacterial entry
  • Is expelled at calving
  • Key Benefits

    No Antibiotic Resistance Concerns

    As a non-antibiotic product, Orbeseal does not contribute to antimicrobial resistance issues.

    Effective for Low-SCC Cows

    Ideal for cows with no existing infections that need protection from new intramammary infections during dry period.

    Long-Duration Protection

    Remains in place throughout extended dry periods.

    Proper Administration

    Technique is Critical

  • Milk out quarter completely
  • Clean and disinfect teat end thoroughly
  • Do NOT insert cannula fully (partial insertion only)
  • Infuse contents slowly
  • Do NOT massage product upward
  • Important: Keep Product Low

    Orbeseal should remain in teat canal and cistern, not be massaged into upper udder tissue.

    Selective Dry Cow Therapy

    Orbeseal enables selective dry cow therapy protocols:

  • Low-SCC cows: Orbeseal alone
  • High-SCC or infected cows: Antibiotic plus Orbeseal
  • Reduces overall antibiotic use on farm
  • At Calving

    Orbeseal typically expels naturally during first milkings. Check streams for any residual material.

    Storage

    Store at room temperature. Do not freeze.

    Key Features

    • Bismuth Subnitrate Formula: Forms durable physical barrier
    • Non-Antibiotic: Supports selective therapy programs
    • Full Dry Period Protection: Remains effective until calving
    • Single Infusion: Applied once at dry-off
    • Visible at Calving: Easy to confirm removal

    Advanced Features

    • Combination Use: Can be used with dry cow antibiotics
    • SDCT Programs: Enables selective dry cow therapy

    Ideal For

    Farm Types: Dairy farms, All housing types

    Competitive Advantages

    What sets Orbeseal Teat Sealant apart from alternatives:

    • Proven effectiveness in preventing dry period infections
    • Supports antibiotic reduction goals
    • FDA approved non-antibiotic option
    • Well-established research base

    Pricing Information

    Here is the pricing information for Orbeseal Teat Sealant:

    Internal teat sealant for dry cow mastitis prevention.

    Pricing Model: Per-tube intramammary sealant

    Orbeseal by Zoetis. Veterinary prescription required. Creates physical barrier against new infections.

    Pros & Considerations

    Advantages:
    • Prevents new infections during dry period
    • Physical barrier protects teat canal
    • Reduces dry period mastitis significantly
    • Easy administration at dry-off
    • Proven efficacy in research trials
    Considerations:
    • Must be used with proper dry-off protocol
    • Cannot treat existing infections
    • Product cost adds to dry-off expenses
    • Requires attention to clean administration

    Implementation & Setup

    How to implement Orbeseal Teat Sealant on your dairy operation:

    Implementation Timeline: Applied at dry-off

    Training & Support

    Training and support options available for Orbeseal Teat Sealant:

    Support Channels:

      Evaluation Questions

      Key questions to consider when evaluating Orbeseal Teat Sealant:

      1. What is your current dry cow therapy protocol?
      2. Are you implementing selective dry cow therapy?
      3. What is your dry period infection rate?
      4. Is your staff trained on proper technique?

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      About Zoetis

      Learn more about Zoetis and their complete product lineup on their company profile page.

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