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Zoetis Spectramast LC

By Zoetis

Last reviewed: December 2025

Spectramast LC provides broad-spectrum mastitis treatment with ceftiofur hydrochloride, offering extended activity against both gram-positive and...

Overview

Spectramast LC (ceftiofur hydrochloride) is a third-generation cephalosporin antibiotic providing extended spectrum coverage against mastitis pathogens in lactating dairy cattle.

Broad Spectrum Coverage

Ceftiofur is effective against:

  • Streptococcus species
  • Staphylococcus aureus (non-beta-lactamase producing)
  • Escherichia coli
  • Klebsiella species
  • Other gram-negative coliforms
  • Key Advantage

    Unlike many mastitis treatments that target primarily gram-positive bacteria, Spectramast LC provides coverage of coliform mastitis, making it valuable for farms with E. coli or Klebsiella challenges.

    Dosage Protocol

    Administration

  • Infuse one tube per affected quarter
  • Continue treatment for up to 8 consecutive days
  • Use after complete milk-out
  • Withdrawal Periods

  • Milk: 72 hours after last treatment
  • Meat: 2 days after last treatment
  • Clinical Applications

    Acute Clinical Mastitis

    Appropriate for moderate to severe clinical mastitis cases, especially when coliform involvement is suspected.

    Culture-Based Treatment

    Ideal choice when cultures indicate gram-negative pathogens.

    Veterinary Guidance

    Work with your herd veterinarian to:

  • Establish treatment protocols
  • Define case selection criteria
  • Monitor treatment outcomes
  • Adjust protocols as needed
  • Responsible Use

    Spectramast LC is an important antibiotic resource. Use it responsibly to:

  • Preserve antibiotic effectiveness
  • Follow label directions precisely
  • Document all treatments
  • Respect withdrawal times
  • Key Features

    • Extended-Spectrum Activity: Effective against major pathogens
    • Ceftiofur Formulation: Third-generation cephalosporin
    • Zero-Day Milk Discard: After labeled withdrawal period
    • Convenient Infusion: Ready-to-use syringe format
    • Proven Efficacy: Established clinical effectiveness

    Advanced Features

    • Multi-Dose Treatment: Protocol for extended therapy
    • Veterinary Partnership: Prescription product for proper use

    Ideal For

    Farm Types: Dairy farms, All housing types

    Competitive Advantages

    What sets Spectramast LC apart from alternatives:

    • Broad spectrum coverage
    • Established efficacy data
    • Convenient packaging
    • Zero-day milk discard (after withdrawal)

    Pricing Information

    Here is the pricing information for Spectramast LC:

    Third-generation cephalosporin for lactating cow mastitis treatment.

    Pricing Model: Per-tube intramammary antibiotic

    Spectramast LC (ceftiofur) by Zoetis. Broad-spectrum coverage. Veterinary prescription required. Short milk withdrawal beneficial for lactating cows.

    Pros & Considerations

    Advantages:
    • Broad-spectrum mastitis treatment
    • Approved for lactating dairy cattle
    • Effective against common mastitis pathogens
    • Cephalosporin efficacy and safety
    • Well-established product
    Considerations:
    • Prescription required
    • Withdrawal periods for milk and meat
    • Cephalosporin stewardship considerations
    • Not all pathogens equally susceptible

    Implementation & Setup

    How to implement Spectramast LC on your dairy operation:

    Implementation Timeline: Used as needed for clinical cases

    Training & Support

    Training and support options available for Spectramast LC:

    Support Channels:

      Evaluation Questions

      Key questions to consider when evaluating Spectramast LC:

      1. What pathogens are common on your farm?
      2. Do you use culture-based treatment?
      3. What are your treatment protocols?
      4. How do you track treatment outcomes?

      Explore Mastitis & Udder Health Treatments

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      About Zoetis

      Learn more about Zoetis and their complete product lineup on their company profile page.

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